Cat. No. 3972
Chemical Name: N1-Ethoxycarbonyl-N4-[(2,4,6-trimet
Biological ActivityPositive allosteric modulator of GABAA receptors. Modulates both α4β3δ-containing extrasynaptic receptors and α1β3γ2S-containing receptors in Xenopus oocytes, displaying a stronger modulatory effect at the former. Reduces motor coordination and exhibits anxiolytic effects in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hoestgaard-Jensen et al (2010) Pharmacological characterization of a novel positive modulator at α4β3δ-containing extrasynaptic GABAA receptors. Neuropharmacology 58 702. PMID: 20060846.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses AA 29504 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: AA 29504, supplier, GABAA, positive, allosteric, modulators, pams, alpha4beta3delta, a4b3d, α4β3γ, anxiolytic, gamma-aminobutyric, acid, AA29504, Tocris Bioscience, GABAA Receptor Modulator products