Cat. No. 3935
Chemical Name: 5-(6,7-Dihydrobenzo[b]thien-4-yl-1H
Biological ActivityAgonist of the α2D adrenergic receptor (Ki values are 1.5, 254, 443 and 621 nM for α2D, α2A, α1 and α2B adrenergic receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Amphoux et al (2010) Inhibitory and facilitatory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1- and α2-adrenoceptor subtypes. Eur.J.Pharmacol. 634 1. PMID: 20170649.
Ross et al (2000) α2 adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a high-affinity ligand for the α2D adrenergic receptor. J.Med.Chem. 43 765. PMID: 10753480.
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Keywords: RWJ 52353, supplier, RWJ52353, agonists, alpha2D, a2d, α2d, adrenergic, receptors, adrenoceptors, Tocris Bioscience, Adrenergic α2 Receptor Agonist products