Ticlopidine hydrochloride

Cat. No. 3931

Ticlopidine hydrochloride C14H14ClNS.HCl [53885-35-1]

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Chemical Name: 5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

Biological Activity

Selective P2Y12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.

Technical Data

M.Wt:
300.25
Formula:
C14H14ClNS.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
53885-35-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Michelson (2008) P2Y12 antagonism: promises and challenges. Arterioscler.Thromb.Vasc.Biol. 28 33.

Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31 174.

Sharis et al (1998) The antiplatelet effects of ticlopidine and clopidogrel. Ann.Int.Med. 129 394.

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Keywords: Ticlopidine hydrochloride, supplier, selective, P2Y12, purinergic, receptors, purinoceptors, antagonists, Tocris Bioscience, Purinergic (P2Y) Receptor Antagonist products

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