Cat. No. 3913
Chemical Name: 4-(7,8,9,10-Tetrahydro-7,7,10,10-te
Biological ActivityRXR agonist. Acts as a retinoid synergist; enhances the potency of AM 80 (Cat. No. 3507) in a HL-60 cell differentiation assay.
Licensing InformationSold under licence.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Ishida et al (2003) Clinically potential subclasses of retinoid synergists revealed by gene expression profiling. Mol.Cancer Ther. 2 49. PMID: 12533672.
Ohashi et al (2002) Effect of natural and synthetic retinoids on the proliferation and differentiation of three canine melanoma cell lines. J.Vet.Med.Sci. 64 169. PMID: 11913557.
Umemiya et al (1997) Regulation of retinoidal actions by diazepinylbenzoic acids. Retinoid synergists which activate the RXR-RAR heterodimers. J.Med.Chem. 40 4222. PMID: 9435893.
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Keywords: HX 630, supplier, HX630, synergists, retinoids, retinoic, pan-RXR, agonists, retinoid, synergist, Tocris Bioscience, Retinoid X Receptor products
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