WAY 208466 dihydrochloride
Cat. No. 3904
Chemical Name: 3-[(-3-Fluorophenyl)sulfonyl]-N,N-d
Biological ActivityHigh affinity, selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor). Elevates cortical GABA levels in vivo in rat frontal cortex. Exhibits antidepressant and anxiolytic-like effects.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Carr et al (2010) Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats. Psychopharmacol.(Berl.) 213 49. PMID: 20217056.
Schechter et al (2008) Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacol 33 1323. PMID: 17625499.
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