SF 11

Cat. No. 3898

SF 11 C27H30N2O2S [443292-81-7]

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Chemical Name: N-(4-Ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide

Biological Activity

NPY Y2 antagonist (IC50 = 199 nM). Displays no affinity for Y1 receptor at concentrations up to 35 μM. Causes significant lethality in mice. Brain penetrant.

Technical Data

M.Wt:
446.6
Formula:
C27H30N2O2S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
443292-81-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Brothers et al (2010) Selective and brain penetrant neuropeptide Y Y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol.Pharmacol. 77 46. PMID: 19837904.

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Keywords: SF 11, supplier, neuropeptide, Y, NPY, Y2, antagonists, SF11, neuropeptides, Tocris Bioscience, NPY Receptor Antagonist products

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