MRS 2768 tetrasodium salt

Cat. No. 3884

MRS 2768 tetrasodium salt C15H16N2O18P4Na4 [1047980-83-5]

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Chemical Name: Uridine-5'-tetraphosphate δ-phenyl ester tetrasodium salt

Biological Activity

Selective P2Y2 agonist (EC50 = 1.89 μM). Displays no affinity for human P2Y4 or P2Y6 receptors.

Technical Data

M.Wt:
728.14
Formula:
C15H16N2O18P4Na4
Solubility:
Soluble in water (supplied pre-dissolved at a concentration of 10mM)
Purity:
>98 %
Storage:
Store at -80°C
CAS No:
1047980-83-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Ko et al (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg.Med.Chem. 16 6319. PMID: 18514530.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for MRS 2768 tetrasodium salt include:

Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050. PMID: 24048730.

Shabir et al (2013) Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium. PLoS Comput Biol 305 F396. PMID: 23720349.

Trabanelli et al (2012) Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation. J Immunol 189 1303. PMID: 22753942.

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View Related Products by Product Action

Keywords: MRS 2768 tetrasodium salt, supplier, selective, P2Y2, agonists, purinergic, receptors, MRS2768, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products

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