MRS 2768 tetrasodium salt
Cat. No. 3884
Chemical Name: Uridine-5'-tetraphosphate δ-phenyl ester tetrasodium salt
Biological ActivitySelective P2Y2 agonist (EC50 = 1.89 μM). Displays no affinity for human P2Y4 or P2Y6 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ko et al (2008) Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg.Med.Chem. 16 6319. PMID: 18514530.
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Citations are publications that use Tocris products. Selected citations for MRS 2768 tetrasodium salt include:
Ilatovskaya et al (2013) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. Am J Physiol Cell Physiol 305 C1050. PMID: 24048730.
Shabir et al (2013) Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium. PLoS Comput Biol 305 F396. PMID: 23720349.
Trabanelli et al (2012) Extracellular ATP exerts opposite effects on activated and regulatory CD4+ T cells via purinergic P2 receptor activation. J Immunol 189 1303. PMID: 22753942.
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Keywords: MRS 2768 tetrasodium salt, supplier, selective, P2Y2, agonists, purinergic, receptors, MRS2768, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products
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