FFN 511

Cat. No. 3878

FFN 511 C17H20N2O2 [1004548-96-2]

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Chemical Name: 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one

Biological Activity

Fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM).

Licensing Information

Sold with the permission of Columbia University

Technical Data

M.Wt:
284.35
Formula:
C17H20N2O2
Solubility:
Soluble to 25 mM in 1eq. HCl and to 5 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
1004548-96-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Gubernator et al (2009) Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals. Science 324 1441. PMID: 19423778.

Zhang et al (2009) Dopamine release at individual presynaptic terminals visualized with FFNs. J.Vis.Exp. 30. PMID: 19721412.

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Citations are publications that use Tocris products.

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