Cat. No. 3855

RuBi-Nicotine C40H44Cl2N8Ru [1256362-30-7]

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Chemical Name: Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2+) dichloride

Biological Activity

Ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.

Licensing Information

Sold under licence from Columbia University

Technical Data

Soluble to 50 mM in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Filevich et al (2010) A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 104 1248. PMID: 20825994.

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Keywords: RuBi-Nicotine, supplier, RuBiNicotine, caged, compounds, nicotinics, cholinergics, acetylcholine, receptors, nAChRs, agonist, excitatory, Tocris Bioscience, Photolysis products

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