1-Oleoyl lysophosphatidic acid sodium salt
Cat. No. 3854
Chemical Name: 1-O-9Z-Octadecenoyl-sn-glyceryl-3-p
Biological ActivityEndogenous agonist of the lysophospholipid receptors LPA1 and LPA2. Inhibits differentiation of neural stem cells (NSCs) into neurons.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lapierre et al (2010) Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival. J.Biol.Chem. 285 25792. PMID: 20551326.
Dottori et al (2008) Lysophosphatidic acid inhibits neuronal differentiation of neural stem/progenitor cells derived from human embryonic stem cells. Stem Cells 26 1146. PMID: 18308941.
van Corven et al (1992) Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Biochem.J. 281 163. PMID: 1731751.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for 1-Oleoyl lysophosphatidic acid sodium salt include:
Ruprecht et al (2015) Cortical contractility triggers a stochastic switch to fast amoeboid cell motility. J Clin Invest 160 673. PMID: 25679761.
Do you know of a great paper that uses 1-Oleoyl lysophosphatidic acid sodium salt from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: 1-Oleoyl lysophosphatidic acid sodium salt, supplier, lysophosphatidic, acid, LPA, lysophospholipid, receptors, LPL-R, agonists, Tocris Bioscience, Lysophosphatidic Acid Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Potent S1P receptor agonist; also immunosuppresentCinacalcet hydrochloride
Calcium-sensing receptor (CaSR) allosteric agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailableAMG 837 hemicalcium salt
Potent free fatty acid receptor 1 (FFA1/GPR40) partial agonistUMB 68
GHB receptor ligandAZD 1283
High affinity P2Y12 antagonistEx 26
Potent and selective S1P1 receptor antagonistZQ 16
Selective GPR84 agonistIHR-Cy3
Potent fluorescent Smo antagonistRo 6842262
Potent LPA1 antagonistAMG 853
Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonistAM 4668
Potent FFA1 (GPR40) agonistCATPB
FFA2 antagonist/inverse agonistOleanolic acid
Selective GPBA receptor (TGR5) partial agonist
April 10 - 13, 2017