Cat. No. 3847
Chemical Name: N-Ethyl-L-glutamine
Biological ActivityAmino acid analog of glutamine and component of green tea. Shown to bind to AMPA, Kainate, NMDA and group I mGlu receptors. Displays neuroprotective effects in vivo. Promotes self-renewal of human embryonic stem cells (hESC).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Desbordes et al (2008) High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell. 2 602. PMID: 18522853.
Egashira et al (2008) Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother.Res. 22 65. PMID: 17705146.
Nagasawa et al (2004) Possible involvement of group I mGluRs in neuroprotective effect of theanine. Biochem.Biophys.Res.Comm. 320 116.
Kakuda et al (2002) Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors. Biosci.Biotechnol.Biochem. 66 2683. PMID: 12596867.
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Keywords: Theanine, supplier, glutamate, glutamine, analogue, receptors, metabotropic, mGlu, NMDA, Kainate, AMPA, ligands, hESC, human, embryonic, stem, cells, Tocris Bioscience, Miscellaneous Glutamate products
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