Theanine

Cat. No. 3847

Theanine C7H14N2O3 [3081-61-6]

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Chemical Name: N-Ethyl-L-glutamine

Biological Activity

Amino acid analog of glutamine and component of green tea. Shown to bind to AMPA, Kainate, NMDA and group I mGlu receptors. Displays neuroprotective effects in vivo. Promotes self-renewal of human embryonic stem cells (hESC).

Technical Data

M.Wt:
174.2
Formula:
C7H14N2O3
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
3081-61-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Desbordes et al (2008) High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell. 2 602. PMID: 18522853.

Egashira et al (2008) Theanine prevents memory impairment induced by repeated cerebral ischemia in rats. Phytother.Res. 22 65. PMID: 17705146.

Nagasawa et al (2004) Possible involvement of group I mGluRs in neuroprotective effect of theanine. Biochem.Biophys.Res.Comm. 320 116.

Kakuda et al (2002) Inhibition by theanine of binding of [3H]AMPA, [3H]kainate, and [3H]MDL 105,519 to glutamate receptors. Biosci.Biotechnol.Biochem. 66 2683. PMID: 12596867.

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Citations are publications that use Tocris products.

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View Related Products by Product Action

Keywords: Theanine, supplier, glutamate, glutamine, analogue, receptors, metabotropic, mGlu, NMDA, Kainate, AMPA, ligands, hESC, human, embryonic, stem, cells, Tocris Bioscience, Miscellaneous Glutamate products

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