Cat. No. 3845
Chemical Name: N-Benzyl-[2-(pyrimidin-4-yl)amino]t
Biological ActivityGreatly enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB 431542 (Cat. No. 1614) and PD 0325901 (Cat. No. 4192). Improves the survival of human embryonic stem cells (hESCs) upon trypsinization.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Xu et al (2010) Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc.Natl.Acad.Sci. USA 107 8129.
Lin et al (2009) A chemical platform for improved induction of human iPSCs. Nat.Methods. 6 805. PMID: 19838168.
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Keywords: Thiazovivin, supplier, stem, cells, reprogramming, dedifferentiation, enhances, enhancers, induces, induced, pluripotent, stem, cells, ipscs, escs, Tocris Bioscience, Reprogramming products
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