Cat. No. 3841
Biological ActivityChymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770. PMID: 19380825.
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Keywords: RETF-4NA, supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Tocris Bioscience, Other Protease Substrate products
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