Cat. No. 3841
Biological ActivityChymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.
(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770. PMID: 19380825.
If you know of a relevant reference for RETF-4NA please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses RETF-4NA from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: RETF-4NA, supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Tocris Bioscience, Other Protease Substrate products