RETF-4NA

Cat. No. 3841

RETF-4NA Ac-Arg-Glu-Thr-Phe-4-Nitroanilide

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Biological Activity

Chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form. Displays selectivity over cathepsin G and chymotrypsin.

Technical Data

M.Wt:
713.75
Formula:
C32H43N9O10
Sequence:
RETF

(Modifications: Arg-1 = N-terminal Ac, Phe-4 = 4-Nitroanilide)

Solubility:
Soluble to 2 mg/ml in 20% acetonitrile / water
Storage:
Store at -20°C
CAS No:
1160928-63-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Raymond et al (2009) α2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generated activity. J.Immunol. 182 5770. PMID: 19380825.

If you know of a relevant reference for RETF-4NA please let us know.

Citations are publications that use Tocris products.

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Keywords: RETF-4NA, supplier, chymase, substrates, selective, angiotensin, II, enzymes, activators, Tocris Bioscience, Other Protease Substrate products

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