NPEC-caged-(S)-AMPA

Cat. No. 3840

NPEC-caged-(S)-AMPA C16H17N3O8 [1257323-84-4]

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Chemical Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Biological Activity

1-(2-nitrophenyl)ethyl caged version of (S)-AMPA (Cat. No. 0254), agonist at the AMPA receptor. Extinction coefficient (ε347) = 660 M-1cm-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.

Technical Data

M.Wt:
379.32
Formula:
C16H17N3O8
Solubility:
Soluble to 5 mM in water with gentle warming and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
1257323-84-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Palma-Cerda et al (2012) New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups. Neuropharmacology. 63 624. PMID: 22609535.

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Keywords: NPEC-caged-(S)-AMPA, supplier, NPEC-caged-(S)-AMPA, caged, compounds, AMPA, receptors, Tocris Bioscience, Photolysis products

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