Cat. No. 3816
Chemical Name: (2β,3β,5β,11α,22R)-2,3,5,11,14,20,22-He
Biological ActivityEcdysone analog that acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bosser and Zornig (2005) Agonists of an ecdysone-inducible mammalian expression system inhibit Fas-ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO. Cell Death Diff. 13 189.
Patrick et al (2001) Muristerone A-induced nerve growth factor release from genetically engineered human dermal fibroblasts for peripheral nerve tissue engineering. Tissue Eng. 7 303. PMID: 11429150.
No et al (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc.Natl.Acad.Sci.USA 93 3346.
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Keywords: Muristerone A, supplier, ecdysone, analogs, analogues, inhibits, antiapoptotic, Bcl-XL, inducing, agents, MuristeroneA, Tocris Bioscience, Bcl-2 Family products
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