Repaglinide

Cat. No. 3805

Repaglinide C27H36N2O4 [135062-02-1]

Price and Availability

For Repaglinide pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: AG-EE 623ZW

Chemical Name: 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid

Biological Activity

Kir6 (KATP) channel blocker that binds with high affinity for SUR1 when co-expressed with Kir6.2 (Kd = 0.42 nM). Antidiabetic glucose regulator with hypoglycaemic effect in vivo.

Technical Data

M.Wt:
452.59
Formula:
C27H36N2O4
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
135062-02-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Hansen et al (2005) Kir6.2-dependent high-affinity repaglinide binding to β-cell KATP channels. Br.J.Pharmacol. 144 551. PMID: 15678092.

Mark and Grell (1997) Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs. Br.J.Pharmacol. 121 1597. PMID: 9283692.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Repaglinide from Tocris? If so please let us know.

View Related Products by Target

Keywords: Repaglinide, supplier, K+, channel, pore, blockers, KATP, Blocks, SUR1, KIR6, Kir6.2, sulphonylurea, receptor, inward, rectifier, Tocris Bioscience, Inward Rectifier Potassium (Kir) Channel Blocker products

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Our Cardiovascular Guide highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

New Products in this Area

BeKm 1

Potent and selective KV11.1 (hERG) channel blocker

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.