Cat. No. 3761
Chemical Name: 2-[(1R)-3-[Bis(1-methylethyl)amino]
Biological ActivityHigh affinity muscarinic receptor antagonist (Ki = 3.3 nM). Active at all muscarinic receptor subtypes (M1 - M5); exhibits a greater effect on the bladder than salivary glands in vivo.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Nilvebrant (2001) Clinical experiences with tolterodine. Life Sci. 68 2549. PMID: 11392625.
Nilvebrant et al (1997) Tolterodine - a new bladder-selective antimuscarinic agent. Eur.J.Pharmacol. 327 195. PMID: 9200560.
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Citations are publications that use Tocris products.
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Keywords: Tolterodine L-tartrate, supplier, high, affinity, muscarinic, receptors, antagonists, M1, M2, M3, M4, M5, acetylcholine, ACh, Pfizer, Tolterodine, L-tartrate, Tocris Bioscience, Non-selective Muscarinic Antagonist products