GSK 264220A

Cat. No. 3752

GSK 264220A C17H21N3O4S [685506-42-7]

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Chemical Name: N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea

Biological Activity

Endothelial lipase and lipoprotein lipase inhibitor (IC50 values are 0.13 and 0.10 μM respectively).

Technical Data

M.Wt:
363.43
Formula:
C17H21N3O4S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
685506-42-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Goodman et al (2009) Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors. Bioorg.Med.Chem.Letts. 19 27.

Keller et al (2008) A high-throughput screen for the endothelial lipase using HDL as substrate. J.Biomol.Screen. 13 468. PMID: 18566479.

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Keywords: GSK 264220A, supplier, GSK264220A, endothelial, lipase, lipoprotein, lipases, inhibitors, inhibits, Tocris Bioscience, Lipase Inhibitor products

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