NCH 51

Cat. No. 3747

NCH 51 C20H26N2O2S2 [848354-66-5]

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Alternative Name: PTACH

Chemical Name: 2-Methylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester

Biological Activity

Histone deacetylase (HDAC) inhibitor. Inhibits growth of various cancer cells in vitro (EC50 = 1.1 - 9.1 μM).

Technical Data

Soluble to 100 mM in DMSO and to 25 mM in ethanol
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Sanda et al (2007) Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cells. Leukemia 21 2344. PMID: 17690692.

Suzuki et al (2005) Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J.Med.Chem. 48 1019. PMID: 15715470.

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Keywords: NCH 51, supplier, NCH51, HDACs, inhibitors, inhibits, histone, deacetylases, epigenetics, Tocris Bioscience, Histone Deacetylase Inhibitor products

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