Cat. No. 3747
Alternative Name: PTACH
Chemical Name: 2-Methylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)a
Biological ActivityHistone deacetylase (HDAC) inhibitor. Inhibits growth of various cancer cells in vitro (EC50 = 1.1 - 9.1 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Sanda et al (2007) Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cells. Leukemia 21 2344. PMID: 17690692.
Suzuki et al (2005) Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J.Med.Chem. 48 1019. PMID: 15715470.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses NCH 51 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: NCH 51, supplier, NCH51, HDACs, inhibitors, inhibits, histone, deacetylases, epigenetics, Tocris Bioscience, Histone Deacetylase Inhibitor products
Find multiple products by catalog number
New Products in this Area
HDAC5 and HDAC9 inhibitorMC 1742
Potent class I and IIb HDAC inhibitorYK 3-237
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.