Cat. No. 3741

Stauprimide C35H28N4O5 [154589-96-5]

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Chemical Name: [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide

Biological Activity

Small molecule that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the efficiency of directed differentiation of mouse and human ESCs in vitro.

Technical Data

Soluble in DMSO
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Zhu et al (2009) A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell. 4 416. PMID: 19427291.

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Keywords: Stauprimide, supplier, embryonic, stem, cells, ESCs, differentiation, inhibitors, inhibits, NME2, nuclear, translocation, transcription, factors, primes, Tocris Bioscience, Other Transcription Factor products

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