Cat. No. 3734
Chemical Name: 4-[(1-Methyl-1H-pyrrol-2-yl)methyle
Biological ActivityPotent and selective poly(ADP-ribose) polymerase (PARP)-1 inhibitor (pIC50 values are 5.38 and 7.35 for PARP-2 and PARP-1 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Eltze et al (2008) Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors. Mol.Pharmacol. 74 1587. PMID: 18809672.
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Citations are publications that use Tocris products. Selected citations for BYK 204165 include:
Hamilton (2014) Cytotoxic effects of fascaplysin against small cell lung cancer cell lines. Lab Chip 12 1377. PMID: 24608973.
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Keywords: BYK 204165, supplier, BYK204165, PARP1, poly(ADP-ribose), polymerases, selective, inhibitors, inhibits, Tocris Bioscience, Poly(ADP-Ribose) Polymerase Inhibitor products