MDL 72527

Cat. No. 3709

MDL 72527 C12H20N2.2HCl [93565-01-6]

Price and Availability

For MDL 72527 pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N1,N4-Di-2,3-butadienyl-1,4-butanediamine dihydrochloride

Biological Activity

Polyamine oxidase (POA) inhibitor. Does not inhibit monoamine oxidase or D-Amino acid oxidase. Displays anticancer and neuroprotective activity in vivo.

Technical Data

M.Wt:
265.23
Formula:
C12H20N2.2HCl
Solubility:
Soluble to 100 mM in water and to 75 mM in DMSO
Storage:
Desiccate at +4°C
CAS No:
93565-01-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Basu et al (2009) A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 69 7689. PMID: 19773450.

Dogan et al (1999) Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion. J.Neurochem. 72 765. PMID: 9930751.

Bey et al (1985) N-2,3-butadienyl-1,4-butanediamine derivatives: potent irreversible inactivators of mammalian polyamine oxidase. J.Med.Chem. 28 1. PMID: 3965702.

If you know of a relevant reference for MDL 72527 please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses MDL 72527 from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: MDL 72527, supplier, MDL72527, polyamine, oxidases, inhibitors, inhibits, POA, Tocris Bioscience, Other Oxygenase/Oxidase Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

Spring/Summer 2017

New Product Guide (Spring/Summer 2017)

Our New Product guide highlights over 130 new products added in the first half of 2017. View PDF today.

divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.