Cat. No. 3700
Alternative Name: R 837
Chemical Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c
Biological ActivityImmunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Averett et al (2007) The pharmacology of endosomal TLR agonists in viral disease. Biochem.Soc.Trans. 35 1468. PMID: 18031247.
Schon and Schon (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr.Med.Chem. 14 681. PMID: 17346155.
Syed et al (2001) A review of the applications of imiquimod: a novel immune response modifier. Exp.Opin.Pharmacother. 2 877.
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Keywords: Imiquimod, supplier, Toll-like, receptors, 7, TLR7, agonists, R837, Tocris Bioscience, Toll-like Receptor Agonist products
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