Cat. No. 3700
Alternative Name: R 837
Chemical Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c
Biological ActivityImmunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Averett et al (2007) The pharmacology of endosomal TLR agonists in viral disease. Biochem.Soc.Trans. 35 1468. PMID: 18031247.
Schon and Schon (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr.Med.Chem. 14 681. PMID: 17346155.
Syed et al (2001) A review of the applications of imiquimod: a novel immune response modifier. Exp.Opin.Pharmacother. 2 877.
If you know of a relevant reference for Imiquimod please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Imiquimod from Tocris? If so please let us know.
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Keywords: Imiquimod, supplier, Toll-like, receptors, 7, TLR7, agonists, R837, Tocris Bioscience, Toll-like Receptor Agonist products
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