Imiquimod

Cat. No. 3700

Imiquimod C14H16N4 [99011-02-6]

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Alternative Name: R 837

Chemical Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Biological Activity

Immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.

Technical Data

M.Wt:
240.3
Formula:
C14H16N4
Solubility:
Soluble to 5 mM in DMSO with gentle warming
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
99011-02-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Averett et al (2007) The pharmacology of endosomal TLR agonists in viral disease. Biochem.Soc.Trans. 35 1468. PMID: 18031247.

Schon and Schon (2007) The antitumoral mode of action of imiquimod and other imidazoquinolines. Curr.Med.Chem. 14 681. PMID: 17346155.

Syed et al (2001) A review of the applications of imiquimod: a novel immune response modifier. Exp.Opin.Pharmacother. 2 877.

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Keywords: Imiquimod, supplier, Toll-like, receptors, 7, TLR7, agonists, R837, Tocris Bioscience, Toll-like Receptor Agonist products

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