5,7-Dichlorokynurenic acid sodium salt
Cat. No. 3698
Chemical Name: 5,7-Dichloro-4-hydroxyquinoline-2-c
Biological ActivitySodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286), a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Baron et al (1990) Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site. Mol.Pharmacol. 38 554. PMID: 2172769.
Moore et al (1990) Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor. Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 5,7-Dichlorokynurenic acid sodium salt from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: 5,7-Dichlorokynurenic acid sodium salt, supplier, Potent, NMDA, antagonists, glycine, site, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
NMDA receptor modulator; metabolite of Ketamine hydrochloride (Cat. No.3131)2S,6S-Hydroxynorketamine hydrochloride
Potent AMPA agonist; antidepressant2R,6R-Hydroxynorketamine hydrochloride
Potent AMPA agonist; lacks ketamine-related side effects(R)-Norketamine hydrochloride
NMDA receptor modulator; metabolite of Ketamine hydrochloride (Cat. No.3131).PEAQX tetrasodium salt
Potent NMDA receptor antagonist; NR2A selective
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.