Kynurenic acid sodium salt

Cat. No. 3694

Kynurenic acid sodium salt C10H6NNaO3 [2439-02-3]

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Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt

Biological Activity

Sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

Soluble to 100 mM in water and to 50 mM in DMSO
>99 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Wang et al (2006) Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35. J.Biol.Chem. 281 22021. PMID: 16754668.

Pittaluga et al (1997) The 'kynurenate test', a biochemical assay for putative cognition enhancers. J.Pharmacol.Exp.Ther. 283 82. PMID: 9336311.

Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Progr.Neurobiol. 30 333.

Perkins and Stone (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 247 184. PMID: 6215086.

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Keywords: Kynurenic acid sodium salt, supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Tocris Bioscience, Non-selective Ionotropic Glutamate Antagonist products

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