DL-AP5 Sodium salt
Cat. No. 3693
Chemical Name: DL-2-Amino-5-phosphonopentanoic acid sodium salt
Biological ActivitySodium salt of DL-AP5 (Cat. No. 0105). Potent NMDA antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378. PMID: 6145492.
Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75 65. PMID: 7042024.
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Citations are publications that use Tocris products. Selected citations for DL-AP5 Sodium salt include:
Pan et al (2016) Postnatal development of the electrophysiological properties of somatostatin interneurons in the anterior cingulate cortex of mice. PLoS One 6 28137. PMID: 27319800.
Thomsen et al (2016) Fixed single-cell transcriptomic characterization of human radial glial diversity. Sci Rep 13 87. PMID: 26524239.
Falgairolle and O'Donovan (2015) Pharmacological Investigation of Fluoro-Gold Entry into Spinal Neurons. Purinergic Signal 10 e0131430. PMID: 26102354.
Do you know of a great paper that uses DL-AP5 Sodium salt from Tocris? If so please let us know.
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Keywords: DL-AP5 Sodium salt, supplier, Broad, spectrum, EAA, antagonists, Glutamate, Ionotropic, Non-Selective, iGluR, Receptors, mGlur, Metabotropic, Tocris Bioscience, NMDA Receptor Antagonist products
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Potent NMDA receptor antagonist; NR2A selective
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