Cat. No. 3692
Chemical Name: 3-Azaspiro[5.5]undecane hydrochloride
Biological ActivityM2 proton channel blocker (IC50 = 0.92 μM). Inhibits influenza virus M2 protein (AM2).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Wang et al (2009) Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from Influenza A Virus. J.Am.Chem.Soc. 131 8066. PMID: 19469531.
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Citations are publications that use Tocris products.
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Keywords: 4,4-Pentamethylenepiperidine hydrochloride, supplier, M2, proton, channels, blockers, influenza, virus, protein, AM2, modulators, Tocris Bioscience, Other Channel Modulator products