4,4-Pentamethylenepiperidine hydrochloride

Cat. No. 3692

4,4-Pentamethylenepiperidine hydrochloride C10H19N.HCl [1125-01-5]

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Chemical Name: 3-Azaspiro[5.5]undecane hydrochloride

Biological Activity

M2 proton channel blocker (IC50 = 0.92 μM). Inhibits influenza virus M2 protein (AM2).

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Wang et al (2009) Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from Influenza A Virus. J.Am.Chem.Soc. 131 8066. PMID: 19469531.

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Keywords: 4,4-Pentamethylenepiperidine hydrochloride, supplier, M2, proton, channels, blockers, influenza, virus, protein, AM2, modulators, Tocris Bioscience, Other Channel Modulator products

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