Cat. No. 3690
Chemical Name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzo
Biological ActivitySelective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Sohn et al (2009) S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic insulin sensitivity in 48 h lipid infused rats. Eur.J.Pharmacol. 608 104. PMID: 19250932.
Carmona et al (2007) S 26948: a new specific peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects. Diabetes 56 2797. PMID: 17704298.
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Keywords: S26948, supplier, Peroxisome, Proliferator-activating, Receptors, PPARg, PPARγ, PPARgamma, agonists, antidiabetic, S26948, Tocris Bioscience, PPARγ Agonist products
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May 17 - 19, 2017