Cat. No. 3690
Chemical Name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzo
Biological ActivitySelective PPARγ agonist (EC50 = 8.83 nM). Drives normal adipocyte differentiation and exhibits a lipid-lowering effect; reduces atherosclerosis in E2-KI mice. Displays antidiabetic properties and improves hepatic insulin sensitivity in intralipid-infusion (IL) rats.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Sohn et al (2009) S26948, a new specific peroxisome proliferator activated receptor gamma modulator improved in vivo hepatic insulin sensitivity in 48 h lipid infused rats. Eur.J.Pharmacol. 608 104. PMID: 19250932.
Carmona et al (2007) S 26948: a new specific peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects. Diabetes 56 2797. PMID: 17704298.
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Keywords: S26948, supplier, Peroxisome, Proliferator-activating, Receptors, PPARg, PPARγ, PPARgamma, agonists, antidiabetic, S26948, Tocris Bioscience, PPARγ Agonist products