Cat. No. 3681
Chemical Name: 5-[Bis(2-chloroethyl)amino]-1-methy
Biological ActivityCytostatic agent that displays activity in non-Hodgkin's lymphomas. Exhibits bifunctionality; combines DNA alkylating properties with those of purine analogs.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Masiello and Tulpule (2009) Bendamustine therapy in chronic lymphocytic leukemia. Expert Opin.Pharmacother. 10 1687. PMID: 19527193.
Keating et al (2008) Bendamustine. Nat.Rev.Drug Discov. 7 473. PMID: 18511926.
Schwanen et al (2002) In vitro evaluation of bendamustine induced apoptosis in B-chronic lymphocytic leukemia. Leukemia. 16 2096. PMID: 12357363.
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Citations are publications that use Tocris products.
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Keywords: Bendamustine hydrochloride, supplier, Cytostatic, agent, exhibits, DNA, alkylating, purine, analogue, properties, apoptosis, inducers, dna, synthesis, inhibitors, inhibits, chemotherapeutics, Tocris Bioscience, Apoptosis Inducing products
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