Teijin compound 1
Cat. No. 3664
Chemical Name: N-[2-[[(3R)-1-[(4-chlorophenyl)meth
Biological ActivityPotent chemokine CCR2b receptor antagonist (IC50 = 180 nM). Potently inhibits cell chemotaxis induced by MCP-1 (EC50 = 24 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hall et al (2009) Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5. Mol.Pharmacol. 75 1325. PMID: 19297521.
Moree et al (2008) Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg.Med.Chem.Letts. 18 1869.
Moree et al (2004) Small molecule antagonists of the CCR2b receptor. Part 2: discovery process and initial structure-activity relationships of diamine derivatives. Bioorg.Med.Chem.Letts. 14 5413.
If you know of a relevant reference for Teijin compound 1 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Teijin compound 1 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Teijin compound 1, supplier, Potent, CCR2b, antagonists, chemokines, receptors, Teijin, compound1, Tocris Bioscience, Chemokine CC Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.