Neurodazine

Cat. No. 3656

Neurodazine C27H21ClN2O3 [937807-66-4]

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Chemical Name: 2-[5-(3-Chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole

Biological Activity

Induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.

Technical Data

M.Wt:
456.92
Formula:
C27H21ClN2O3
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
937807-66-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Halder et al (2015) Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons. Chem.Biol. 22 1512. PMID: 26590637.

Williams et al (2007) Synthetic small molecules that induce neurogenesis in skeletal muscle. J.Am.Chem.Soc. 129 9258. PMID: 17622149.

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Keywords: Neurodazine, supplier, Neurodazine, stem, cells, neurogenesis, mature, human, skeletal, muscle, cells, C2C12, myoblasts, neurogenics, Tocris Bioscience, Reprogramming products

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