Cat. No. 3652
Chemical Name: (3α,5β)-3-Hydroxy-pregnan-20-one
Biological ActivityGABAA receptor positive allosteric modulator. Neuroactive steroid.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Morris et al (1999) Differential modulation of the γ-aminobutyric acid type C receptor by neuroactive steroids. Mol.Pharmacol. 56 752. PMID: 10496958.
Harrison et al (1987) Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346. PMID: 3033209.
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Citations are publications that use Tocris products.
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Keywords: Pregnanolone, supplier, GABAA, receptors, positive, allosteric, modulators, neuroactive, steroid, Tocris Bioscience, GABAA Receptor Modulator products
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September 27 - 30, 2017