Pregnanolone

Cat. No. 3652

Pregnanolone C21H34O2 [128-20-1]

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Chemical Name: (3α,5β)-3-Hydroxy-pregnan-20-one

Biological Activity

GABAA receptor positive allosteric modulator. Neuroactive steroid.

Technical Data

M.Wt:
318.49
Formula:
C21H34O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store at RT
CAS No:
128-20-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Morris et al (1999) Differential modulation of the γ-aminobutyric acid type C receptor by neuroactive steroids. Mol.Pharmacol. 56 752. PMID: 10496958.

Harrison et al (1987) Structure-activity relationships for steroid interaction with the γ-aminobutyric acidA receptor complex. J.Pharmacol.Exp.Ther. 241 346. PMID: 3033209.

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Citations are publications that use Tocris products.

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Keywords: Pregnanolone, supplier, GABAA, receptors, positive, allosteric, modulators, neuroactive, steroid, Tocris Bioscience, GABAA Receptor Modulator products

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