Phospho-Glycogen Synthase Peptide-2 (substrate)

Cat. No. 1352

Phospho-Glycogen Synthase Peptide-2 (substrate) Tyr-Arg-Arg-Ala-Ala-Val-Pro-Pro-Ser-Pro-Ser-Leu-Ser-Arg-His-Ser-Ser-Pro-His-Gln-Ser(OPO3H2)-Glu-Asp-Glu-Glu-Glu

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Alternative Name: GS peptide-2

Biological Activity

Synthetic peptide suitable as a substrate for glycogen synthase kinase-3 (GSK-3).

Technical Data

M.Wt:
3029
Formula:
C123H191N40O48P
Sequence:
YRRAAVPPSPSLSRHSSPHQSEDEEE

(Modifications: Ser-21 = OPO3H2)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
851366-97-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Sutherland et al (1993) Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth factor signalling. Biochem.J. 296 15. PMID: 8250835.

Woodgett (1989) Use of peptide substrates for affinity purification of protein-serine kinases. Anal.Biochem. 180 237. PMID: 2554753.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Phospho-Glycogen Synthase Peptide-2 (substrate) include:

Stoothoff et al (2005) FRAT-2 preferentially increases glycogen synthase kinase 3 β-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation. PLoS One 280 270. PMID: 15522877.

Do you know of a great paper that uses Phospho-Glycogen Synthase Peptide-2 (substrate) from Tocris? If so please let us know.

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Keywords: Phospho-Glycogen Synthase Peptide-2 (substrate), supplier, GSK-3, synthetic, Glycogen, synthase, kinase-3, kinases, Carbohydrate, Metabolism, Enzyme, Substrates, Activators, GSpeptide2, Tocris Bioscience, Enzyme Substrate / Activator Substrate products

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