des-Gln14-Ghrelin (rat)

Cat. No. 1346

des-Gln14-Ghrelin (rat) Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg

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Biological Activity

An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH release in vivo.

Licensing Information

This peptide is distributed under license from Dr. Kangawa

Technical Data

M.Wt:
3186.7
Formula:
C142H237N43O40
Sequence:
GSSFLSPEHQKAQRKESKKPPAKLQPR

(Modifications: Ser-3 = Ser(n-octanoyl))

Solubility:
Soluble to 2 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
293735-04-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Hosoda et al (2000) Purification and characterization of rat des-Gln14-ghrelin, a second endogenous ligand for the growth hormone secretagogue receptor. J.Biol.Chem. 275 21995. PMID: 10801861.

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Keywords: des-Gln14-Ghrelin (rat), supplier, Endogenous, ghrelin, receptor, ligands, GHS-R1a, Receptors, Growth, Hormone, Secretagog, Receptor, 1a, Tocris Bioscience, Ghrelin Receptor products

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