Cat. No. 3639
Chemical Name: 6-Chloro-5-[[4-[(4-fluorophenyl)met
Biological ActivityPotent p38α inhibitor (IC50 = 9 nM). Also inhibits p38β and JNK-2 (IC50 values are 90 nM and 100 nM respectively). Displays no significant activity at p38γ, p38δ, ERK-2 and JNK-1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lee and Dominguez (2005) MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38α protein. Curr.Med.Chem. 12 2979. PMID: 16378500.
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Keywords: SX 011, supplier, SX011, p38, inhibitors, inhibits, MAPK, p38alpha, p38beta, p38a, p38b, signaling, signalling, Mitogen-Activated, Protein, Kinases, Tocris Bioscience, p38 MAPK Inhibitor products
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