cAMPS-Sp, triethylammonium salt
Cat. No. 1333
Chemical Name: (S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
Biological ActivityCell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor. Enantiomer cAMPS-Rp, triethylammonium salt (Cat. No. 1337) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Lin et al (2006) Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology 51 747. PMID: 16806304.
Kawasaki et al (1998) A family of cAMP-binding proteins that directly activate Rap1. Science 282 2275. PMID: 9856955.
Dostmann et al (1990) Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem. 265 10484. PMID: 2162349.
O'Brian et al (1982) A kinetic study of interactions of (Rp)- and (Sp)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry 21 4371. PMID: 6289880.
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Citations are publications that use Tocris products. Selected citations for cAMPS-Sp, triethylammonium salt include:
Keng et al (2012) Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats. J Biomed Sci 19 11. PMID: 22300389.
Do you know of a great paper that uses cAMPS-Sp, triethylammonium salt from Tocris? If so please let us know.
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Keywords: cAMPS-Sp, triethylammonium salt, supplier, Cell-permeable, cAMP, Cyclic, adenosines, Monophosphate, Tocris Bioscience, cAMP products