Cat. No. 1342
Chemical Name: (1-Pentyl-1H-indol-3-yl)-1-naphthal
Biological ActivityPotent cannabinoid receptor agonist with mild selectivity for CB2 (Ki values are 2.94 and 9.0 nM for CB2 and CB1 receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Huffman et al (2003) 3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor. Bioorg.Med.Chem. 11 539. PMID: 12538019.
Aung et al (2000) Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend. 60 133. PMID: 10940540.
Chin et al (1999) The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor. J.Pharmacol.Exp.Ther. 291 837. PMID: 10525107.
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Keywords: JWH 018, supplier, Potent, CB1, CB2, agonists, Cannabinoids, Non-Selective, Receptors, JWH018, cb2r, cb1r, Tocris Bioscience, Non-selective Cannabinoid Agonist products
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