QX 222

Cat. No. 1043

QX 222 C13H21ClN2O [5369-00-6]

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Chemical Name: 2-[(2,6-Dimethylphenyl)amino]-N,N,N-trimethyl-2-oxoethaniminium chloride

Biological Activity

Sodium channel blocker.

Technical Data

M.Wt:
256.77
Formula:
C13H21ClN2O
Solubility:
Soluble to 100 mM in water
Storage:
Store at RT
CAS No:
5369-00-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Cuevas and Adams (1994) Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. Br.J.Pharmacol. 11 663. PMID: 7517326.

Hanck et al (1994) Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study. J.Gen.Physiol. 103 19. PMID: 8169596.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for QX 222 include:

Li et al (2005) Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother 49 388. PMID: 15616319.

Slesinger (2001) Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels. Biophys J 80 707. PMID: 11159438.

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Keywords: QX 222, supplier, Na+, channel, blockers, Sodium, NaV, Channels, voltage-gated, voltage-dependent, QX222, Tocris Bioscience, Voltage-gated Sodium (NaV) Channel Blocker products

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