Cat. No. 3611

Lys-gamma3-MSH Lys-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-Arg-Arg-Asn-Ser-Ser-Ser-Ser-Gly-Ser-Ser-Gly-Ala-Gly-Gln

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Biological Activity

Pro-opiomelanocortin (POMC) derived peptide. Potentiates the steriodogenic action of corticotrophin on the adrenal cortex, possibly via the MC3 receptor. Potently stimulates lipolysis via activation of hormone-sensitive lipase (HSL).

Technical Data

Soluble to 1 mg/ml in 10% acetonitrile / water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Bicknell et al (2009) Lys-gamma3-MSH: a global regulator of hormone-sensitive lipase activity? Mol.Cell.Endocrinol. 300 71. PMID: 18977407.

Harmer et al (2008) Evidence of a possible role fo Lys-γ3-MSH in the regulation of adipocyte function. J.Endocrinol. 196 149. PMID: 18180326.

Harmer and Bicknell (2004) The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal. Endocrine Res. 30 629.

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Keywords: Lys-gamma3-MSH, supplier, Pro-opiomelanocortin, POMC, hormone-sensitive, lipase, activators, HSL, melanocortin, receptors, Hydrolases, Lys-γ3-MSH, Lys-gamma3-MSH, Lys-γ3-Melanocyte-stimulating, Lys-gamma3-Melanocyte-stimulating, hormone, Tocris Bioscience, Melanocortin (MC) Receptor products

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Appetite Modulation

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