Cat. No. 3609
Chemical Name: 5-(Chloro-N-(4,5-dihydro-1H-imidazo
Biological Activityα2-adrenergic receptor agonist. Antinociceptive upon epidural administration in rats (IC50 = 48 nM). Also binds to imidazoline receptor.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Asano et al (2000) Antinociception by epidural and systemic α2-adrenoceptor agonists and their binding affinity in rat spinal cord and brain. Anesth.Analg. 90 400. PMID: 10648329.
Piletz et al (2000) Autoradiographic comparison of [3H]-Clonidine binding to non-adrenergic sites and α2-adrenergic receptors in human brain. Neuropsychopharmacology 23 697. PMID: 11063925.
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