RS 56812 hydrochloride
Cat. No. 0988
Chemical Name: (R)-N-(1-Azabicyclo[2.2.2]oct-3-yl)
Biological ActivityA highly potent and selective 5-HT3 partial agonist, with a pKi at 5-HT3 receptors in rat brain of 9.6, and greater than 1000-fold selectivity over a wide range of other neurotransmitter receptors.
Licensing InformationSold with the permission of Roche Bioscience
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Clark et al (1995) N-(Quinuclidin-3-yl)-2-(1-methyl-1H-indol-3-yl)-2-oxoacetamide: a high affinity 5-HT3 receptor partial agonist. Bioorg.Med.Chem.Lett. 5 1853.
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Citations are publications that use Tocris products. Selected citations for RS 56812 hydrochloride include:
Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Mol Psychiatry 7 2336. PMID: 26114334.
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