CP 93129 dihydrochloride
Cat. No. 1032
Chemical Name: 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4
Biological ActivityPotent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.
Licensing InformationSold for research purposes under agreement from Pfizer Inc.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hamid et al (2014) Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex. J Neurosci. 34 260. PMID: 24381287 .
Lee et al (1998) Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats. Psychopharmacology 136 304. PMID: 9566817.
Koe et al (1992) Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253. Drug Development Research 26 241.
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