RS 16566 dihydrochloride

Cat. No. 1015

RS 16566 dihydrochloride C18H23ClN4O.2HCl [1217788-97-0]

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Chemical Name: (R)-N-1-Azabicyclo[2.2.2]oct-3-yl-6-chloro-1-(1-methylethyl)-1H-benzimidazole-4-carboxamide

Biological Activity

High affinity ligand for the (R)-zacopride binding site (pKi 9.84 ).

Licensing Information

Sold with the permission of Roche Bioscience

Technical Data

M.Wt:
419.78
Formula:
C18H23ClN4O.2HCl
Solubility:
Soluble to 10 mM in water
Purity:
>98 %
Storage:
Store at RT
CAS No:
1217788-97-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Flippin et al (1996) (R)-3-(6-Chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: a high affinity ligand for the (R)-zacopride binding site. Bioorg.Med.Chem.Lett. 6 477.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for RS 16566 dihydrochloride include:

Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. J Neurosci 7 2336. PMID: 26114334.

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