Cat. No. 1019
Chemical Name: [3S-(3α,4aα,6β,8aα)]-Decahydro-6-(phosp
Biological ActivityCompetitive NMDA receptor antagonist.
Licensing InformationSold with the permission of Eli Lilly and Company.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Borowicz et al (1996) Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice. Epilepsia 37 618. PMID: 8681893.
Ellison (1994) Competitive and non-competitive NMDA antagonists induce similar limbic degeneration. Neuroreport 5 2688. PMID: 7696633.
If you know of a relevant reference for LY 235959 please let us know.
Citations are publications that use Tocris products. Selected citations for LY 235959 include:
Fowler et al (2011) Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature 471 597. PMID: 21278726.
Kenny et al (2009) NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala. Neuropsychopharmacology 34 266. PMID: 18418357.
Do you know of a great paper that uses LY 235959 from Tocris? If so please let us know.
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Keywords: LY 235959, supplier, Competitive, NMDA, antagonist, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, LY235959, Tocris Bioscience, NMDA Receptor Antagonist products