Cat. No. 1009
Chemical Name: (RS)-α-Ethyl-4-carboxyphenylglycine
Biological ActivityNovel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG (Cat. No. 0336).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493. PMID: 8730745.
Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323. PMID: 8719814.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for E4CPG include:
Newman (2005) Calcium increases in retinal glial cells evoked by light-induced neuronal activity. Neuropharmacology 25 5502. PMID: 15944378.
Do you know of a great paper that uses E4CPG from Tocris? If so please let us know.
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Keywords: E4CPG, supplier, Group, II, group, I, mGlur, antagonists, Receptors, mGlu2, mGlu3, mGluR2, mGluR3, Glutamate, Metabotropic, mGlu1, mGlu5, mGluR1, mGluR5, Tocris Bioscience, Glutamate (Metabotropic) Group I Receptor Antagonist products