RuBi-4AP

Cat. No. 3557

RuBi-4AP C30H28Cl2N8Ru [851956-02-0]

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Alternative Name: Rubi-4-aminopyridine

Chemical Name: bis(2,2'-Bipyridine-N,N')bis(4-aminopyridine-N1) ruthenium(2+) dichloride complex

Biological Activity

Water soluble ruthenium-bipyridine-triphenylphosphine caged 4-aminopyridine (4-AP). Excited by visible wavelengths and has two-photon uncaging capabilities under physiological conditions. Releases 4-AP (Cat. No. 0940), a voltage-dependent K+ channel blocker.

Licensing Information

Sold under licence from Columbia University

Technical Data

M.Wt:
672.58
Formula:
C30H28Cl2N8Ru
Solubility:
Soluble to 30 mM in water
Storage:
Store at -20°C
CAS No:
851956-02-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Nikolenko et al (2005) Two-photon uncaging of neurochemicals using inorganic metal complexes. Chem.Commun. 13 1752.

Zayat et al (2003) A new strategy for neurochemical photodelivery: Metal-ligand heterolytic cleavage. J.Am.Chem.Soc. 125 882. PMID: 12537482.

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Keywords: RuBi-4AP, supplier, voltage-dependent, gated, K+, potassium, channel, blockers, caged, 4-aminopyridine, hERG, Human, Ether-A-Go-Go, Gene, KCNQ, Tocris Bioscience, Voltage-gated Potassium (KV) Channel Blocker products

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