Cat. No. 3556
Alternative Name: COR 167
Chemical Name: N-(Adamant-1-yl)-6-isopropyl-4-oxo-
Biological ActivityPotent and selective CB2 receptor agonist (Ki values are 6.3 nM and 1.2 μM for CB2 and CB1 receptors respectively). Displays analgesic activity in the formalin test in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Contartese (2012) A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury. Pharmacol.Res. 66 555. PMID: 23036353.
Pasquini et al (2008) Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. J.Med.Chem. 51 5075. PMID: 18680276.
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Keywords: SER 601, supplier, Potent, selective, CB2, receptors, agonists, analgesic, cannabinoids, SER601, cb2r, COR, 167, COR167, Tocris Bioscience, CB2 Receptor Agonist products
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December 13 - 15, 2016