Cat. No. 3552
Chemical Name: N-[[4-(1,1-Dimethylethyl)phenyl]met
Biological ActivityPotent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). Displays selectivity over K+, Na+ and L-type Ca2+ channels. Prevents tonic seizures in the audiogenic seizure model in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Hu et al (1999) Structure-activity relationships of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers. Bioorg.Med.Chem.Letts. 9 2151.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses PD 173212 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: PD 173212, supplier, Potent, N-type, Ca2+, channel, blockers, Calcium, CaV, Channels, voltage-gated, voltage-dependent, PD173212, Tocris Bioscience, Voltage-gated Calcium Channel (CaV) Blocker products
Find multiple products by catalog number
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands