Cat. No. 3552
Chemical Name: N-[[4-(1,1-Dimethylethyl)phenyl]met
Biological ActivityPotent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). Displays selectivity over K+, Na+ and L-type Ca2+ channels. Prevents tonic seizures in the audiogenic seizure model in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hu et al (1999) Structure-activity relationships of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers. Bioorg.Med.Chem.Letts. 9 2151.
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Keywords: PD 173212, supplier, Potent, N-type, Ca2+, channel, blockers, Calcium, CaV, Channels, voltage-gated, voltage-dependent, PD173212, Tocris Bioscience, Voltage-gated Calcium Channel (CaV) Blocker products
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October 30 - November 3, 2016
Boston, MA, USA