Cat. No. 0963
Chemical Name: 9-Anthracenecarboxylic acid
Biological ActivityCl- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac IcI.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pusch et al (2006) Channel or transporter? The CLC saga continues. Exp.Physiol. 91 149. PMID: 16179405.
EstÚvez et al (2003) Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron 38 47. PMID: 12691663.
Gadsby et al (1995) The CFTR chloride channel of mammalian heart. Annu.Rev.Physiol. 57 387. PMID: 7539989.
Cabantchik and Greger (1992) Chemical probes for anion transporters of mammalian cell membranes. Am.J.Physiol. 262 C803-C827. PMID: 1566811.
If you know of a relevant reference for 9-AC please let us know.
Citations are publications that use Tocris products. Selected citations for 9-AC include:
Freeman et al (2013) Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors. Online J Biol Sci 110 103. PMID: 23576702.
Li et al (2005) Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother 49 388. PMID: 15616319.
Do you know of a great paper that uses 9-AC from Tocris? If so please let us know.
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Keywords: 9-AC, supplier, Chloride, transport, inhibitors, inhibits, Cl-, Channels, CFTR, Tocris Bioscience, Other Chloride Channel Inhibitor products