Cat. No. 1004
Chemical Name: 5-(4-Chlorophenyl)-4-methyl-3-(1-(2
Biological ActivityA potent and highly selective D4 dopamine receptor antagonist, with Ki values of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors.
Licensing InformationSold with the permission of Merck Sharp and Dohme Ltd.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Rowley et al (1997) 4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor. J.Med.Chem. 40 2374. PMID: 9240352.
Rowley et al (1996) 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors. J. Med. Chem. 39 1943. PMID: 8642551.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses L-741,742 hydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: L-741,742 hydrochloride, supplier, selective, D4, antagonists, Dopamine, Receptors, dopaminergic, L741742, Tocris Bioscience, D4 Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.